import tkinter
def my_window(w, h):
ws = root1.winfo_screenwidth();
hs = root1.winfo_screenheight();
x = (ws/2) - (w/2);
y = (hs/2) - (h/2);
root1.geometry('%dx%d+%d+%d'%(w, h, x, y));
root1 = tkinter.Tk(className='python windows app')
my_window(640, 480);
root1.mainloop();
无废话,撸起袖子就是,干!